The Analgesic Efficacy of Perineural Nalbuphine as an Adjuvant to Bupivacaine in Ultrasound Guided Superficial Cervical Plexus Nerve Block for Thyroid Surgeries. A Double Blinded Randomized Controlled Trial.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
This study aiming to evaluate the analgesic effect of adding nalbuphine as an adjuvant to bupivacaine in superficial cervical plexus block during thyroid surgeries regarding first rescue analgesia in the first twenty-four hours postoperative, VAS score after extubation and complications such as postoperative nausea, vomiting and respiratory depression.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:
• Patients aged between 18 to 60 years old of both sexes undergoing elective thyroid surgery.
• ASA I and II.
Locations
Other Locations
Egypt
Kasr Alainy Teaching Hospitals
RECRUITING
Giza
Contact Information
Primary
Sara M Badie, Master degree
sarabadie1993@gmail.com
0109588821
Backup
Nashwa Nabil, Professor
nashwanabeel@yahoo.com
01001111968
Time Frame
Start Date: 2024-07-15
Estimated Completion Date: 2025-07
Participants
Target number of participants: 54
Treatments
Placebo_comparator: Group (C) control group
Patients will receive bilateral superficial cervical plexus block with 28 ml bupivacine 0.25% mixed with 2 ml saline 0.9%, to a volume of 30 ml, 15 ml on each side of the neck before induction of general anaesthesia.
Active_comparator: Group (N) Perineural Nalbuphine
Patients will receive bilateral superficial cervical plexus block with 28 ml Bupivacaine 0.25% mixed with 10 mg nalbuphine in saline 0.9% to a volume of 30 ml, 15 ml on each side of the neck before induction of general anaesthesia.
Related Therapeutic Areas
Sponsors
Leads: Cairo University