Preoperative Acetazolamide for Improved Pain Control Following Laparoscopic Hysterectomy
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 21
Maximum Age: 65
Healthy Volunteers: f
View:
• Women
• Ages 21-65
• undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without bilateral salpingoophorectomy
• undergoing total laparoscopic hysterectomy (TLH) for benign indications with or without cystoscopy
Locations
United States
South Carolina
Prisma Health
RECRUITING
Greenville
Contact Information
Primary
Patti Parker, BSN
patti.parker@prismahealth.org
864-455-1510
Backup
Paul Miller, MD
paul.miller@prismahealth.org
864-455-1600
Time Frame
Start Date: 2025-10-30
Estimated Completion Date: 2026-11-01
Participants
Target number of participants: 100
Treatments
Active_comparator: Active Drug
Acetazolamide 500mg ER
Active_comparator: Placebo
Inactive Placebo Capsule
Related Therapeutic Areas
Sponsors
Leads: Prisma Health-Upstate