The Effect of Dexamethasone Administration Route in Infraclavicular Brachial Plexus Block for Pediatric Arm and/or Hand Surgery

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

This study aims to assess the impact of the administration route of dexamethasone (intravenous vs. perineural) on postoperative pain and inflammatory response in pediatric patients undergoing hip surgery. The primary outcome is postoperative pain intensity measured using an age-appropriate scale at multiple intervals. Secondary outcomes include inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), opioid consumption, time-to-first rescue analgesia, and overall patient recovery. This randomized, double-blinded study seeks to improve pain management strategies and optimize anesthesia protocols in pediatric arm surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3 months
Maximum Age: 6
Healthy Volunteers: f
View:

• children scheduled for arm/wrist/hand surgery

• body weight \> 5kg

Locations
Other Locations
Poland
Poznan University of Medical Sciences
RECRUITING
Poznan
Poznan University of Medical Sciences
NOT_YET_RECRUITING
Poznan
Contact Information
Primary
Malgorzata Reysner, M.D. Ph.D.
mreysner@ump.edu.pl
+48 61 873 83 03
Time Frame
Start Date: 2025-10-01
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 90
Treatments
Active_comparator: perinerual dexamethasone
infraclavicular brachial plexus block + perineural dexamethasone
Active_comparator: intravenous dexamethasone
infraclavicular brachial plexus block + intravenous dexamethasone
Placebo_comparator: 0.2ml/kg 0.2% ropivacaine
infraclavicular brachial plexus block
Related Therapeutic Areas
Sponsors
Leads: Poznan University of Medical Sciences

This content was sourced from clinicaltrials.gov