Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Early Phase 1
SUMMARY

The goal of this clinical trial is to compare the efficacy of bupivacaine and ropivacaine in third molar removal surgery under general anesthesia in healthy volunteers. The main question aims to determine whether there is any difference in vital signs, hemostasis and postoperative pain between ropivacaine and bupivacaine in patients undergoing third molars extraction under general anesthesia. Researchers will compare bupivacaine and ropivacaine in a split-mouth study to determine if one drug is more effective in third molar extraction surgery under general anesthesia (better hemostasis, less postoperative pain, and fewer changes in vital signs). Participants will undergo a single surgical procedure and complete the Visual Analog Scale to record postoperative pain

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: t
View:

• Patients aged 18 to 60

• Patients ASA Physical Status Classification I and II

• Patients with impacted or semi-impacted lower third molars with similar positioning on both sides according to the Pell and Gregory classification

Locations
Other Locations
Brazil
Hospital de Clínicas de Porto Alegre
RECRUITING
Porto Alegre
Contact Information
Primary
Henrique T Oliveira
htedesco99@gmail.com
55 51999601939
Time Frame
Start Date: 2025-07-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 15
Treatments
Active_comparator: Group A - Bupivacaine
use of bupivacaine 0,5% + epinephrine 0,2mL in third molar surgery in general anesthesia
Active_comparator: Group B - Ropivacaine
use of ropivacaine 0,75% + epinephrine 0,2mL in third molar surgery in general anesthesia
Related Therapeutic Areas
Sponsors
Leads: Henrique Tedesco

This content was sourced from clinicaltrials.gov

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