Clinical Study on the Therapeutic Efficacy of Biportal Endoscopic Decompression Spine Surgery and Lumbar Decompression Fusion Surgery in the Treatment of Degenerative Lumbar Spondylolisthesis

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This study aims to systematically evaluate the therapeutic efficacy of dual-channel endoscopic spinal decompression versus lumbar decompression with fusion for degenerative lumbar spondylolisthesis. Patients undergoing either procedure will undergo detailed preoperative and postoperative follow-up to compare outcomes between the two techniques, specifically assessing postoperative pain relief, neurological improvement, and the incidence of surgical complications.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 90
Healthy Volunteers: f
View:

• Aged between 50 and 90 years old with a confirmed diagnosis of degenerative lumbar spondylolisthesis;

• Clinical symptoms include chronic pain, nerve compression, or motor dysfunction, confirmed by imaging studies (e.g., MRI or CT);

• No significant improvement after at least 3 months of conservative treatment (e.g., medication, physical therapy), meeting surgical indications;

• Understand and consent to the relevant procedures of this study, and sign the informed consent form.

Locations
Other Locations
China
4th Affiliated Hospital, School of Medicine, Zhejiang University
RECRUITING
Yiwu
Contact Information
Primary
xiang xue, MD
xuexiang@zju.edu.cn
+86 057989935990
Time Frame
Start Date: 2025-12-10
Estimated Completion Date: 2030-06-30
Participants
Target number of participants: 100
Treatments
UBE
Only decompression
Fusion
Lumbar Spine Fusion Surgery
Related Therapeutic Areas
Sponsors
Leads: The Fourth Affiliated Hospital of Zhejiang University School of Medicine

This content was sourced from clinicaltrials.gov