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Evaluation of Postoperative Analgesic Efficacy of Ultrasound-Guided Rectus-Intercostal Fascial Plane Block in Living Liver Donors

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Postoperative pain control plays a crucial role in enhancing recovery and improving early mobilization in living liver donors. The rectus-intercostal fascial plane (RIFP) block is a novel ultrasound-guided regional anesthesia technique that provides anterior abdominal wall analgesia by targeting the intercostal nerves between the rectus abdominis and intercostal muscle fascia. This prospective, randomized controlled clinical study aims to evaluate the postoperative analgesic efficacy and opioid-sparing effects of the RIFP block compared with standard intravenous analgesia in living liver donors undergoing donor hepatectomy. Participants will be randomly assigned to two groups: Group 1 (RIFP Block): Patients receiving an ultrasound-guided rectus-intercostal fascial plane block using 20 mL of 0.25% bupivacaine at the end of surgery, in addition to standard IV PCA (morphine). Group 2 (Control): Patients receiving only standard IV PCA (morphine) without regional block.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Age between 18 and 75 years

• Patients with American Society of Anesthesiology (ASA) physical status I-II

• Patients scheduled for a living donor hepatectomy

Locations
Other Locations
Turkey
istinye University
RECRUITING
Istanbul
Contact Information
Primary
Taylan Sahin
taylansah@hotmail.com
+905452303111
Time Frame
Start Date: 2025-12-22
Estimated Completion Date: 2026-06
Participants
Target number of participants: 64
Treatments
Active_comparator: Rectus Intercostal Plane Block Group
Rectus Intercostal Plane Block Group The patients in the Rectus Intercostal Plane Block group will receive a bilateral rectus intercostal plane block and patient-controlled analgesia (PCA) with morphine for postoperative analgesia.
Active_comparator: Control Group
The patients in the Control group will not receive any regional block and will receive PCA with morphine for postoperative analgesia.
Related Therapeutic Areas
Sponsors
Leads: Istinye University

This content was sourced from clinicaltrials.gov

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