Comparison of Pain Relief by Bupivacaine With Dexmedetomidine and Bupivacaine Alone in Transversus Abdominis Plane Block for Postoperative Analgesia in Patients Undergoing Abdominal Surgeries.

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study investigates the effectiveness of adding dexmedetomidine to bupivacaine for postoperative analgesia in patients undergoing abdominal surgeries. The research compares pain relief in two groups: one receiving a combination of bupivacaine and dexmedetomidine via a transversus abdominis plane (TAP) block, and the other receiving bupivacaine alone. The study aims to evaluate whether dexmedetomidine enhances pain relief, reduces the need for additional pain medication, and impacts sedation and side effects such as hypotension, bradycardia, and nausea. Conducted at Sheikh Zayed Medical College in Rahim Yar Khan, Pakistan, the trial will involve 80 participants and will measure pain using the Visual Analogue Scale (VAS), along with monitoring other vital parameters and complications over 12 hours post-surgery. The primary objective is to determine if the addition of dexmedetomidine provides superior pain control without significantly increasing side effects.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 45
Healthy Volunteers: f
View:

• Age between 21 to 45 years.

• Undergoing elective abdominal surgery (exploratory laparotomy, ileostomy reversal, laparoscopic/open cholecystectomy, mesh repair of paraumbilical hernias).

• The patient must be capable of providing informed consent.

Locations
Other Locations
Pakistan
Sheikh Zayed Medical College
RECRUITING
Rahim Yar Khan
Contact Information
Primary
Rameesha Musharaf, FCPS ANESTHESIA (PGR)
rameeshamusharaf96@gmail.com
0092-334-5038000
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2025-12
Participants
Target number of participants: 80
Treatments
Experimental: Bupivacaine + Dexmedetomidine (TAP Block)
Participants in this arm will receive a combination of 20 ml of 0.25% bupivacaine and 1 mcg/kg dexmedetomidine administered via an ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management following abdominal surgery
Active_comparator: Bupivacaine Only (TAP Block)
Participants in this arm will receive 20 ml of 0.25% bupivacaine administered via an ultrasound-guided transversus abdominis plane (TAP) block for postoperative pain management following abdominal surgery
Related Therapeutic Areas
Sponsors
Leads: Sheikh Zayed Medical College

This content was sourced from clinicaltrials.gov