Acute Pain Clinical Trials

Find Acute Pain Clinical Trials Near You

Comparative Efficacy of 4 mg vs. 8 mg Submucosal Dexamethasone in Postoperative Pain Management After Dental Implant Surgery: A Randomized Double-Blind Controlled Clinical Trial

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

This study aims to compare the effectiveness of 4mg and 8mg dexamethasone administered submucosally in reducing postoperative pain after dental implant surgery. Participants will be randomly assigned to receive either 4mg dexamethasone, 8mg dexamethasone, or a placebo (normal saline) at the surgical site. Later, postoperative pain will be assessed using a Visual Analog Scale at 6 hours after the surgery and daily for the next 6 days. Also the number of pain-relief tablets consumed after the surgery will be recorded. Preoperative anxiety will be assessed using Generalized Anxiety Disorder-7 (GAD-7) questionnaire to assess its association with postoperative pain scores. The results of this study will help determine the optimal dose of dexamethasone that is effective for postoperative pain control following dental implant surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 80
Healthy Volunteers: f
View:

• Males \& females

• Age range (21-80)

• ASA I \& II according to (American Society of Anesthesiologists) classification

• Single tooth implant

• Type 3 \& type 4 implant placement timing (Chen and Buser, 2009)

Locations
Other Locations
Oman
Al Nahdha Hospital
RECRUITING
Muscat
Contact Information
Primary
Shurooq Slim Al Hinai, BDS
shurooqalhinai@gmail.com
+968 96148103
Backup
Nasser Al Khaldi, Senior Consultant Prosth
dent2020@gmail.com
+ 968 92898987
Time Frame
Start Date: 2026-03-25
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 138
Treatments
Experimental: 8mg Dexamethasone
8mg/2ml dexamethasone injection.
Experimental: 4mg Dexamethasone
4mg/1ml Dexamethasone ampoule + 1ml of sterile normal saline for injection. Mixing dexamethasone with sterile normal saline for injection is considered safe and has no effect on drug potency and efficacy based on current evidence.
Placebo_comparator: Placebo
2 ml of sterile normal saline for injection.
Related Therapeutic Areas
Sponsors
Leads: Oman Ministry of Health

This content was sourced from clinicaltrials.gov