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Comparison of Transdiscal and Paravertebral Approaches for Neurolytic Splanchnic Nerve Block in the Treatment of Upper Abdominal Cancer Pain

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to compare the efficacy of fluoroscopy-guided paravertebral (PV) and transdiscal (TD) approaches for splanchnic nerve neurolysis in patients with upper abdominal cancer-related pain (e.g., gastric, pancreatic, and hepatic malignancies). Treatment response will be assessed using the Numerical Rating Scale (NRS), and the impact of both techniques on quality of life will be evaluated with the EORTC QLQ-C30 questionnaire.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Severe abdominal pain (NRS \> 6) due to upper intra-abdominal organ malignancies (such as gastric, pancreatic, or hepatic cancer).

• Failure of pain control with conservative treatment modalities.

Locations
Other Locations
Turkey
Ankara Etlik City Hospital
RECRUITING
Ankara
Contact Information
Primary
Gokhan Yildiz
gkoyldz@gmail.com
5059272589
Time Frame
Start Date: 2026-02-16
Estimated Completion Date: 2026-09-16
Participants
Target number of participants: 56
Treatments
Active_comparator: transdiscal splanchnic neurolysis group
Transdiscal splanchnic neurolysis for upper gastrointestinal malignancy pain
Active_comparator: paravertebral splanchnic neurolysis group
Paravertebral splanchnic neurolysis for upper gastrointestinal malignancy pain
Related Therapeutic Areas
Sponsors
Leads: Ankara Etlik City Hospital

This content was sourced from clinicaltrials.gov

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