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Effect of Adaptive AI-based Virtual Reality on Quality of Recovery and Hospital Stay After Major Abdominal Surgery

Status: Completed
Location: See location...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Major abdominal surgery is frequently associated with postoperative pain, anxiety, delayed recovery, and prolonged hospitalization. This study aims to evaluate the effectiveness of an AI-personalized virtual reality (VR) intervention as an adjunct to routine postoperative care in improving recovery outcomes among patients undergoing major abdominal surgery. Participants assigned to the intervention group receive immersive VR sessions delivered through a smartphone-based head-mounted display integrated with an AI-assisted personalization system. The system combines patient-reported pain and anxiety levels, postoperative recovery status, emotional state estimates obtained through facial emotion recognition technology, and previous session feedback to personalize VR content and enhance patient engagement. VR sessions are initiated on the first postoperative day and administered twice daily until hospital discharge. The primary outcome is postoperative quality of recovery measured using the Quality of Recovery-15 (QoR-15) questionnaire. Secondary outcomes include pain intensity, anxiety, recovery milestones, opioid requirements, simulator sickness, and length of hospital stay. The study compares AI-personalized VR plus routine postoperative care with routine postoperative care alone. Findings from this trial will help determine whether AI-enhanced VR is a feasible, safe, and effective strategy for improving postoperative recovery and reducing hospital stay following major abdominal surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Adult patients aged 18 to 60 years.

• Scheduled for elective major abdominal surgery (e.g., colorectal, gastric, or hepatobiliary procedures).

• Physical and cognitive ability to provide informed consent.

• Ability to use and interact with Virtual Reality (VR) equipment (head-mounted display).

• Followed the standardized Enhanced Recovery After Surgery (ERAS) protocol at the hospital.

Locations
Other Locations
Egypt
Alexandria University Hospital, Faculty of Nursing
Alexandria
Time Frame
Start Date: 2026-03-28
Completion Date: 2026-06-30
Participants
Target number of participants: 84
Treatments
Experimental: AI-Personalized Virtual Reality (VR) Group
Participants received routine postoperative care plus an AI-personalized virtual reality intervention delivered through a smartphone-based head-mounted display. The intervention used facial emotion recognition, pain and anxiety assessments, postoperative status, and previous session feedback to personalize VR content. Sessions were administered twice daily from postoperative day 1 until hospital discharge.
Active_comparator: Control Group
Patients in this group will receive only the standard perioperative care according to the established Enhanced Recovery After Surgery (ERAS) protocol, without any VR exposure or distraction therapy.
Related Therapeutic Areas
Sponsors
Leads: Alexandria University

This content was sourced from clinicaltrials.gov