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Comparison of the Analgesic Effects of Transversalis Fascia Plane Block in Renal Transplantation Surgery

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Renal transplantation is a major surgical procedure associated with significant postoperative pain, particularly due to lower abdominal incision, deep tissue dissection, and extensive surgical manipulation. Effective postoperative pain control is therefore of great importance in this patient population, as inadequate analgesia may impair early mobilization, delay recovery, increase opioid consumption, and contribute to opioid-related adverse effects. In addition, optimal analgesic management may improve patient comfort and support enhanced postoperative outcomes. Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications. In this study; it was aimed to compare the analgesic effectiveness of transversalis fascia plane block in the postoperative period in patients who underwent renal transplantation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Patients aged 18-65 years

• American Society of Anesthesiologists (ASA) score III

• Body Mass Index (BMI) between 18-30 kg/m2

Locations
Other Locations
Turkey
Atakan Sezgi
RECRUITING
Altındağ
Contact Information
Primary
Atakan Sezgi
kansezgi@gmail.com
00905323327000
Backup
Jülide Ergil
julideergil@hotmail.com
00905323469216
Time Frame
Start Date: 2026-04-27
Estimated Completion Date: 2027-10-18
Participants
Target number of participants: 50
Treatments
Active_comparator: Transversalis Fascia Plane Block Group
After the linear ultrasound (US) probe will be placed transversely above the iliac crest on the side of surgery, the abdominal wall muscle layers will be identified and the probe will be moved posteriorly until the transversus abdominis muscle and the transversalis fascia are visualized. A block needle will then be advanced using an in-plane technique, and after negative aspiration, 30 ml of 0.25% bupivacaine hydrochloride will be injected into the fascial plane between the transversus abdominis muscle and the transversalis fascia. Proper spread of the local anesthetic in this plane will be confirmed by ultrasound imaging.~This procedure will be performed unilaterally on the surgical side. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.
Active_comparator: Control Group
Participants in the control group will not receive any regional block intervention.~The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.
Related Therapeutic Areas
Sponsors
Leads: Ankara Etlik City Hospital

This content was sourced from clinicaltrials.gov

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