Partial Neuromuscular Blockade in Acute Hypoxemic Respiratory Failure
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
PNEUMA is a preliminary safety and feasibility trial of a novel approach to the titration of neuromuscular blockade (NMB) to safe spontaneous breathing in patients with moderate to severe acute hypoxemic respiratory failure (AHRF) supported with invasive mechanical ventilation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients supported on invasive mechanical ventilation for moderate to severe AHRF (PaO2/FiO2 \< 150 mm Hg or FiO2 ≥ 60% with an SpO2 ≤ 97% or receiving venovenous extracorporeal membrane oxygenation)
Locations
Other Locations
Canada
University Health Network
RECRUITING
Toronto
Contact Information
Primary
Glauco M. Plens, MD, PhD
glauco.plens@uhn.ca
4373299590
Time Frame
Start Date: 2020-10-01
Estimated Completion Date: 2027-03-01
Participants
Target number of participants: 23
Treatments
Experimental: Partial NMB
Related Therapeutic Areas
Sponsors
Leads: University Health Network, Toronto