Effect of Individualized High Positive End-expiratory Pressure on Postoperative Pulmonary Rate in Laparoscopic Bariatric Surgeries

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
Healthy Volunteers: t
View:

• Patients were eligible for participation if the met the following criteria

‣ Age between 18 and 60 years old.

⁃ Body mass index \> 40

⁃ Laparoscopic bariatric elective surgery under general anesthesia.

⁃ ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC.

Locations
Other Locations
Egypt
Ain shams university
RECRUITING
Cairo
Contact Information
Primary
wessam selima, MD
w.z.selima@med.asu.edu.eg
+201001958858
Backup
ghada sharafeldin, MSc
ghadasharaf.92@gmail.com
+201159296642
Time Frame
Start Date: 2023-10-01
Estimated Completion Date: 2025-05-01
Participants
Target number of participants: 50
Treatments
Experimental: titrate PEEP
individulaized PEEP starting 7cmH2O titrated to best static compliance (Cstat) ranging from 50 -100 cmH2O
Active_comparator: standard
standard PEEP of 5 cmH2O
Sponsors
Leads: Ain Shams University

This content was sourced from clinicaltrials.gov