Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
Mechanical ventilation in ARDS requires protective ventilation with low VT and PEEP. PEEP titration can improve lung recruitment in the dependent lung but with a risk of overdistension in the non-dependant lung. EIT can measure the distribution of tidal ventilation and assess overdistension and collapse during a PEEP titration in any position (prone or not). This study aims to measure the best PEEP as a compromise between recruitment and overdistension during a PEEP trial with EIT before and just after PP.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients hospitalized in the ICU and who suffered moderate or severe ARDS (Berlin criteria, PaO2/FiO2\<150), intubated sedated, under myorelaxant and equipped with EIT
• Over the age of 18.
Locations
Other Locations
France
CH Cote Basque
RECRUITING
Bayonne
Hopital Haut-Lévêque
RECRUITING
Pessac
Contact Information
Primary
Benjamin REPUSSEAU, Dr
benjamin.repusseau@chu-bordeaux.fr
05 57 65 68 66
Time Frame
Start Date: 2024-10-15
Estimated Completion Date: 2026-05
Participants
Target number of participants: 20
Treatments
Study group
Patients with moderate or severe ARDS treated with PP equipped with EIT will be included.~Measurement of EIT data and ventilator spirometry in supine position and just after turning the patient in PP during a decremental PEEP-EIT titration, will be done, and blood gases and finally haemodynamic data
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Bordeaux