Physiological Effects of Lung Impedance Tomography-guided and Plat Pressure-guided Phigh During Airway Pressure Release Ventilation in Patients With Acute Respiratory Distress Syndrome
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Diagnosed with ARDS according to the 2023 global new definition of ARDS.
• Age ≥ 18 years.
Locations
Other Locations
China
Wuhan Union hospital
RECRUITING
Wuhan
Contact Information
Primary
jing Xiao Zou
249126734@qq.com
+862785351606
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 26
Treatments
Experimental: Intervention group
EIT-guided Phigh settings during APRV
No_intervention: Control group
Pplat-guided Phigh settings during APRV
Related Therapeutic Areas
Sponsors
Collaborators: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Leads: XiaoJing Zou,MD