Hydrocortisone Versus Prednisolone for Treatment of Adrenal Insufficiency Disease (HYPER-AID Study)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This study is designed to collect data on individuals with adrenal insufficiency who are changing treatments from hydrocortisone to prednisolone, or vice versa. It will compare anthropometric, biochemical and subjective health outcomes between both treatments.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 85
View:
• Aged 18 - 85 years
• Male or female
• Diagnosed with adrenal insufficiency (AI) for over 6 months according to standard diagnostic criteria
• Established on stable hydrocortisone or prednisolone replacement, dose not altered for at least 4 months
• Individuals taking other hormone replacements are accepted providing that their replacement doses have not altered for at least 3 months;
• Individuals who are able and willing to give written informed consent to participate in the study
Locations
Other Locations
United Kingdom
Imperial College Healthcare NHS Trust
RECRUITING
London
Contact Information
Primary
Sirazum Choudhury, MBBS MRCP
steroids@imperial.ac.uk
07555717544
Time Frame
Start Date: 2018-05-24
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 100
Treatments
Adrenal insufficiency
Individuals who are in the process of changing their treatment from:~1. hydrocortisone to prednisolone or;~2. prednisolone to hydrocortisone
Related Therapeutic Areas
Sponsors
Leads: Imperial College London