Acupuncture for Nasal Congestion in Allergic Rhinitis: An Open-Label, Randomized, Monocenter Trial (ANCAR Trial)

Status: Completed
Location: See location...
Intervention Type: Drug, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Allergic rhinitis (AR) is a disorder that affects more than 500 million people worldwide. Nasal congestion is one of the most general and bothersome symptoms in rhinitis, which affects the quality of life (QOL). Current medications are undesirable due to their side-effects. Acupuncture for AR in general can be considered as safe and can be seen as a potential therapeutic intervention for nasal congestion. Evidence supported that acupuncture is clinically used for signs and symptoms of nose disorders, such as nasal congestion, with effectiveness, but whether acupuncture has immediate, post-treatment and long-term effects on nasal congestion in AR is not verified by strictly designed clinical study. The ANCAR trial uses a standard treatment protocol with a fixed set of acupuncture points - to be as scientific as possible from Western medical viewpoint - to open the nose and affect underlying energetic imbalance and immunity at the same time, to maintain its nose opening effect. This novel acupuncture treatment protocol can be seen as a solid and profound approach from which every AR patient may benefit.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Diagnosed AR by a physician

• Have one of the AR types: seasonal (SAR) or perennial (PAR) or mixed (MAR) allergic rhinitis

• VAS nasal congestion: 3-10

• Age: from 18 years

• Signed Informed Consent

Locations
Other Locations
Netherlands
Mermaid Medicine®
The Hague
Time Frame
Start Date: 2023-04-20
Completion Date: 2023-12-22
Participants
Target number of participants: 11
Treatments
Experimental: Acupuncture arm
Fixed set of acupuncture points
Active_comparator: Control (Carelastin®) arm
Carelastin® (1 mg/ml) azelastine nasal spray, 1 spray puff (0.14 ml) per nostril twice daily (totally 0.56 ml per day)
Related Therapeutic Areas
Sponsors
Collaborators: Affiliated Hospital of Nanjing University of Chinese Medicine, Mermaid Medicine®
Leads: Johanna Maria Vermeulen

This content was sourced from clinicaltrials.gov