Preliminary Application and Evaluation of Exhaled Breath Condensate Biomarkers in Combined Allergic Rhinitis and Asthma Syndrome (CARAS)
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
To explore the differences in the expression of biomarkers in different sample types between the healthy population and different subgroups of the disease, and to screen for potential biomarkers in a more simple, direct and objective way. To screen the biomarkers that can be identified by CARAS Chinese medicine symptoms and different stages, and to provide a reference basis for individualised diagnosis and treatment of the disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:
• Patients with AR, BA and CARAS who meet the Western medical diagnostic criteria;
• Chinese medical evidence consistent with lung qi deficiency evidence, phlegm-heat congestion of the lung evidence, or wind-heat offending the lung evidence;
• Age 18 to 80 years;
• Voluntarily accepted the study and signed an informed consent form;
• Not participated in other clinical studies within 1 month before enrollment.
Locations
Other Locations
China
The First Affiliated Hospital of Henan University of Chinese Medicine
RECRUITING
Henan
Contact Information
Primary
Yang Xie
xieyanghn@163.com
13526621325
Time Frame
Start Date:2023-04-01
Estimated Completion Date:2025-05-30
Participants
Target number of participants:270
Treatments
acute exacerbation CARAS
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
chronic persistence CARAS
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
clinical control CARAS
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
acute exacerbation BA
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
chronic persistence BA
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
clinical control BA
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
intermittent AR
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
persistent AR
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.
healthy individuals
Thirty subjects were included. No intervention was performed and only relevant patient information, blood and exhaled breath condensate were collected.