Confirmatory Study on the Efficacy and Safety of the Fixed-dose Combination of Desloratadine/Betamethasone Versus Desloratadine as Treatment in Patients With Allergic Rhinitis

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

Phase IIIb , longitudinal, multicenter, randomized, double-blind, to evaluate efficacy and safety of the fixed-dose combination of Desloratadine 5 mg / Betamethasone 0.25 mg versus Desloratadine 5 mg monotherapy as treatment for symptoms associated with allergic rhinitis.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Willing to participate in the study and able to provide written informed consent.

• Clinical diagnosis (based on medical history and physical examination) of active allergic rhinitis at study entry.

• Patients presenting with moderate to severe nasal symptoms, with a Total Nasal Symptom Score (TNSS) ≥5.

• In the case of women of childbearing potential who are sexually active, the use of an acceptable contraceptive method (barrier and/or hormonal), as determined by the investigator.

• In the opinion of the Principal Investigator or treating physician, the patient is indicated for treatment with the investigational product and may derive clinical benefit from it.

Locations
Other Locations
Mexico
Laboratorio Silanes, S.A. de C.V.
RECRUITING
Mexico City
Contact Information
Primary
Jorge A Gonzalez, PhD
jogonzalez@silanes.com.mx
5254883785
Backup
Yulia Romero-Antonio, B.S.
yromero@silanes.com.mx
5254883785
Time Frame
Start Date: 2024-11-11
Estimated Completion Date: 2025-06-11
Participants
Target number of participants: 70
Treatments
Experimental: Group A: Desloratadine 5 mg + Betamethasone 0.25 mg
Administered orally, one tablet a day, for 10 days.
Active_comparator: Group B: Desloratadine 5 mg
Administered orally, one tablet a day, for 10 days.
Related Therapeutic Areas
Sponsors
Leads: Laboratorios Silanes S.A. de C.V.

This content was sourced from clinicaltrials.gov

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