Association Analysis Between Variants of COL4A3/COL4A4/COL4A5 and Alport Syndrome in the Han Chinese Population
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Alport syndrome (AS) is caused by pathogenic variants in the type IV collagen genes COL4A3, COL4A4, and COL4A5. This study aims to enroll families and patients with a history of renal hematuria in 27 hospitals and detect these three genes for AS screening. This study also aims to analysis the effect of COL4A3/COL4A4/COL4A5 genotype on the development of kidney disease.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Age: up to 99 Years (Child, Adult, Older Adult)
• Sex: All;
• Families and patients with a history of renal hematuria;
• Those who signed the informed consent.
Locations
Other Locations
China
China Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.
RECRUITING
Shanghai
Time Frame
Start Date: 2021-01-01
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 8165
Related Therapeutic Areas
Sponsors
Leads: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine