Exploring Research on Early Warning Indicators of Protein in Patients With Mild Cognitive Impairment and Alzheimer's Disease
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
This study intends to adopt standardized and rigorous cross-sectional research, collect biological specimens (including blood, feces, urine, saliva and tongue coating) from eligible subjects, and use liquid chromatography/mass spectrometry (LC-MS/MS) technology to explore early warning indicators of protein in patients with mild cognitive impairment and Alzheimer's disease
Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Healthy Volunteers: t
View:
• Older than 55-year-old，male or female.
• patients meet the diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease(AD) or whose family members were diagnoed with AD
• Complete self-rating scale for memory impairment (AD-8 scale)
• Those who agree to participate in clinical research and sign informed consent.
Locations
Other Locations
China
Guangdong Province Hospital of Tradtional Chinese Medicine
RECRUITING
Guangzhou
Contact Information
Primary
jianwen guo, Dr
306247680@qq.com
13724899379
Time Frame
Start Date: 2021-06-01
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 650
Treatments
Healthy control group
aged ≥55 years old, no dementia, MCI or no family history of AD.
Alzheimer's disease high-risk group
aged ≥55 years old, immediate family members of AD patients
Alzheimer's disease group
aged ≥55 years old, diagnosed as AD patients
Mild cognitive impairment group
patients ≥55 years of age, diagnosed with MCI
Related Therapeutic Areas
Sponsors
Leads: Guangzhou University of Traditional Chinese Medicine
Collaborators: Guangzhou Cadre Health Management Center