Cognition and NeuroImaging in neuroDegenerative Disorders (CogNID)
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
This prospective study aims: 1. to compare cognitive performance in different clinical groups of participants with mild cognitive impairment (MCI) or mild dementia \[Alzheimer's Disease (AD), Vascular Cognitive Impairment (VCI) and Fronto-temporal Dementia (FTD)\] to determine whether scores reveal differential profiles between the groups, 2. to demonstrate differences in imaging markers between different dementia syndromes and healthy volunteers using ultra high-field MRI at 7T.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Ability to give informed consent.
• Either pathological, genetic or imaging biomarker evidence to suggest Fronto-temporal Lobar Degeneration, Alzheimer's Disease or Vascular Cognitive Impairment, or defined clinical diagnoses.
Locations
Other Locations
United Kingdom
Nottingham University Hospitals NHS Trust
RECRUITING
Nottingham
Nottinghamshire Healthcare NHS Foundation Trust
COMPLETED
Nottingham
Contact Information
Primary
Akram Dr Hosseini
Akram.Hosseini@nuh.nhs.uk
0115 924 9924
Backup
Pauline Hyman-Taylor
pauline.hyman-taylor@nuh.nhs.uk
0115 924 9924
Time Frame
Start Date: 2018-12-12
Estimated Completion Date: 2025-03
Participants
Target number of participants: 125
Treatments
Cognitive assessments
Neurocognitive assessments, Birmingham Cognitive Screen
MRI at 3T
Brain Imaging: MRI at 3T
MRI at 7T
Brain imaging: Ultrahigh Field MRI at 7T
Related Therapeutic Areas
Sponsors
Leads: Nottingham University Hospitals NHS Trust