PASOS: Physical and Cognitive Aging Study in Older Adults

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Hispanic Americans are the fastest growing older adult group in the United States, disproportionally increasing the risk of an Alzheimer's disease and related dementias diagnosis. Efforts to reduce this risk and mitigate the related cognitive/physical declines are critical. The aim of this study is to assess the feasibility of enrolling older adults into an aging trajectory cohort, while generating preliminary data on associations of physical and cognitive aging trajectories. Our secondary objective is to generate preliminary data on the association of standard measures of physical activity and physical function with cognitive status. This study fits within our longitudinal research goal to reduce dementia incidence by understanding the mechanisms that drive the cognitive-physical aging trajectory.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 55
Maximum Age: 85
Healthy Volunteers: t
View:

⁃ • Hispanic and non-Hispanic adults age 55-85 years, at least 8th grade education, community dwelling.

⁃ Additional Inclusion for Hispanic Americans

• Self-identify as Hispanic American

• Report Spanish as primary language • No evidence of dementia or mild cognitive impairment based on cognitive screening \[i.e., Montreal Cognitive Assessment (MoCA) administered during Visit 1; ≥26 among non-Hispanic White, ≥25 among Hispanics, ≥24 among non-Hispanic Blacks (Milani et al., 2018)\]

Locations
United States
Florida
University of Florida, College of Medicine-Jacksonville
RECRUITING
Jacksonville
Contact Information
Primary
Stacey Alvarez-Alvarado, PhD, MS
salvarezalvarado@ufl.edu
904-244-9937
Time Frame
Start Date: 2025-03-19
Estimated Completion Date: 2027-09-20
Participants
Target number of participants: 100
Treatments
Adult Cohort; n=100 (50 Hispanic American adults and 50 non-Hispanic American adults)
The participants in this PASOS pilot will include 50 self-identified HA individuals and 50 self-identified non-HA individuals between the ages of 55-85 years, with no psychometric evidence of neuropsychological decline. We plan to enroll an equal number of women and men. Race and ethnicity in this study will be determined via self-report or self-identification by participants.
Related Therapeutic Areas
Sponsors
Leads: University of Florida

This content was sourced from clinicaltrials.gov