Self-sampling to Optimize Anal Lesion Outcomes (SOLO)
The purpose of this research study is to find ways to increase anal cancer screening among people at increased risk for anal cancer. This study will try to find out if persons will do an intervention (self-sampling of the anal canal) and if it affects cytology and high-resolution anoscopy (HRA) appointment attendance. Secondarily, the study will assess if a person who gets their choice of either self-sampling or healthcare provider sampling affects clinic attendance.
• Age ≥ 35 years for those who are HIV-positive or ≥ 45 years for those who are HIV-negative.
• Must be either:
‣ A cisgender or transgender sexual minority man, or
⁃ A transgender woman who has sex with men.
• Resides in Chicago, Houston, or Milwaukee metropolitan area.
• Is willing to attend a study clinic.
• Speak and understand either English or Spanish
• Ability to understand a written informed consent document, and the willingness to sign it.