Probing and Modulating Motor Imagery Capacities in Aphantasia

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The present study aims to characterize and modulate motor imagery abilities in individuals with aphantasia. The investigators will characterize the neurophysiological and physiological underpinnings of mental imagery abilities in participants with aphantasia by investigating several indices of motor imagery abilities and comparing them to participants with typical mental imagery abilities. The investigators will investigate whether non-invasive brain stimulation applied to the primary motor cortex improves mental imagery abilities in participants with aphantasia.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• For the aphantasia group only: congenital aphantasia defined as a life-long inability to generate mental imagery (confirmed by a total score of 32 or less on the VVIQ, which is the gold standard questionnaire for aphantasia)

• For the no-aphantasia group only: typical mental imagery capacities (confirmed by a total score of more than 32 on the VVIQ)

• Covered by public health insurance

• Understanding the French language

• Signed written informed consent after being informed about the study

Locations
Other Locations
France
Centre Hospitalier le Vinatier
RECRUITING
Bron
Contact Information
Primary
Lydie SARTELET
lydie.sartelet@ch-le-vinatier.fr
0 437915531
Time Frame
Start Date: 2024-03-28
Estimated Completion Date: 2028-01-01
Participants
Target number of participants: 40
Treatments
Experimental: active stimulation group: 20 participants with aphantasia will receive a session of active HD-tDCS
Participants will receive a session of active HD-tDCS at a current intensity of 4 mA for a duration of 15min. The placement of electrodes will be determined to specifically target the primary motor cortex (4 x 1 montage with the anode over C4). During the stimulation, participants will be engaged in a mental training task (sequential finger tapping-task).
Placebo_comparator: placebo stimulation group: 20 participants with aphantasia will receive a session of sham HD-tDCS
High-definition transcranial direct current (HD-tDCS), sham condition. Participants will receive a session of sham HD-tDCS, which will be delivered following the same procedures as active HD-tDCS but the intensity of the current will be set at 4mA during the 30 first seconds at the beginning of the 15-min period of the stimulation, and equal to 0 mA for the reminding period of stimulation to simulate the tingling sensation often experienced by individuals during active stimulation.~The placement of electrodes will be determined to specifically target the primary motor cortex (4 x 1 montage with the anode over C4). During the stimulation, participants will be engaged in a mental training task (sequential finger tapping-task).
Related Therapeutic Areas
Sponsors
Leads: Hôpital le Vinatier

This content was sourced from clinicaltrials.gov

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