Characterisation of Appendiceal Cancer by Genomic and Transcriptomic Analysis and Correlation With Clinical Outcomes

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Patients ≥ 18 years old who have been diagnosed with appendiceal cancer with peritoneal metastases, have had cytoreductive surgery, have availability of archival tumour tissue and have consented to our institutional biobank program or have a waiver of consent for deceased patients who have not had the opportunity to provide biobank consent (requested at the time of ethics review). Descriptive analysis of the proportion of genetic mutations identified in appendiceal cancers. This is given by the percentage of pathogenic mutations in the peritoneal metastasis compared to the primary tumour.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Participants are eligible to be included in the study only if all of the following criteria apply:

• Patients ≥ 18 years old who have been diagnosed with appendiceal cancer with peritoneal metastases,

• have had cytoreductive surgery

• have availability of archival tumour tissue

Locations
Other Locations
United Kingdom
The Christie NHS Foundation Trust
RECRUITING
Manchester
Contact Information
Primary
Richa Garvia
removed_due_to_spam@email.com
01614463000
Backup
Richa Ms Garvia
removed_due_to_spam@email.com
01614463000
Time Frame
Start Date: 2024-02-04
Estimated Completion Date: 2025-07-03
Participants
Target number of participants: 100
Treatments
All participants
Appendiceal Cancer Patients
Authors
Related Therapeutic Areas
Sponsors
Collaborators: University of Manchester
Leads: The Christie NHS Foundation Trust

This content was sourced from clinicaltrials.gov

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