Biology of Cerebral Arteriovenous Malformations : Study of the Link Between Blood Biomarkers and the Haemorrhagic Prognosis of Cerebral Arteriovenous Malformations

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation. The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke. The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.

Eligibility
Participation Requirements
Sex: All
View:

• Patient over 18 years old

• Patient with a cerebral AVM for which an intervention (endovascular treatment or surgery) or only clinical monitoring

• Express consent to participate in the study

⁃ And

• children

• Free informed and express consent of both holders of the minor patient's parental authority, or, by way of derogation and only if the other holder of parental authority cannot give his or her consent within a time limit compatible with the methodological requirements specific to the conduct of the research with regard to its purposes, of one of the two holders of parental authority

Locations
Other Locations
France
Fondation Ophtalmologique Rotschild
RECRUITING
Paris
Contact Information
Primary
Amélie Yavchitz
ayavchitz@for.paris
01 48 63 64 54
Backup
Jean Philippe DESILLES
jp.desilles@for.paris
Time Frame
Start Date: 2018-11-20
Estimated Completion Date: 2028-11-19
Participants
Target number of participants: 300
Sponsors
Leads: Fondation Ophtalmologique Adolphe de Rothschild

This content was sourced from clinicaltrials.gov