Patient-specific Planning of Minimally Invasive Brain Interventions Based on Vascular-hemodynamic Mapping

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

Endovascular procedures for treating brain aneurysms and arteriovenous malformations (AVMs) are becoming increasingly popular due to their less invasive nature and lower risk of complications. However, they still face challenges such as difficult catheter navigation and incomplete embolization. This study aims to improve the efficiency and safety of endovascular procedures by developing new preoperative planning methodologies. These methodologies involve mapping the cerebral vasculature and creating computational fluid dynamics (CFD) and artificial intelligence (AI) models to simulate blood flow. By using these models, interventional radiologists can better plan catheter navigation and predict embolization outcomes. This could lead to faster, more accurate procedures with reduced radiation exposure for patients.

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Subjects who are diagnosed with aneurysm or arteriovenous malformation

• Subjects who are treated (or will be treated) with endovascular embolization and/or arteriovenous coiling

• During and before/after the subject's intervention, medical images (MRI, 3D rotational angiography, DSA) were collected of the cerebral arterial vascular tree (which can be used to develop patient-specific models), including catheter location and use of contrast fluid to visualize the cerebral to make the arterial tree more visible.

Locations
Other Locations
Belgium
University Hospital Ghent
RECRUITING
Ghent
Contact Information
Primary
Peter Vanlangenhove, Prof. Dr.
peter.vanlangenhove@uzgent.be
+32 9 3323112
Time Frame
Start Date: 2024-08-13
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 500
Treatments
Intracranial aneurysms
Patients with at least one intracranial aneurysm that has been coiled
Arteriovenous malformations
Patients with a cerebral arteriovenous malformation that has been treated by endovascular embolisation
Sponsors
Collaborators: University Ghent
Leads: University Hospital, Ghent

This content was sourced from clinicaltrials.gov

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