Effect of RIVAroxaban in Reducing Radial Artery Occlusion Rate After Transradial Coronary Catheterization

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The purpose of the RIVA-RAO study is to determine whether the use of Rivaroxaban is an effective treatment of radial artery occlusion (RAO) after cardiac catheterization (both angiography and PCI). This is a prospective, single-center, randomized controlled, open-label study that will randomize patients with RAO into two groups, one receiving Rivaroxaban and the other receiving no anticoagulation. RAO will be detected by radial artery ultrasound up to 24 hours after the procedure. Study objectives: Primary objective: To evaluate the effect of treatment with Rivaroxaban, in patients (both symptomatic and asymptomatic) with RAO after a coronary catheterization procedure (both angiography and percutaneous coronary intervention-PCI), in improving patency rates of the radial artery at 4 weeks after the procedure, compared with no-anticoagulation treatment. Secondary objectives: To compare local access site and systemic complications (bleeding events, pseudoaneurysm, arteriovenous fistula) at 4 weeks after the procedure between the two groups.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients (both male and female) undergoing a coronary catheterization procedure (both angiography and PCI) through the transradial access and having successfully received at least one radial artery sheath of any size at the end of the procedure

• Radial artery occlusion confirmed by ultrasound (2D, Doppler, colour)

Locations
Other Locations
Greece
AHEPA University Hospital
RECRUITING
Thessaloniki
Contact Information
Primary
Matthaios Didagelos, MD, MSc, PhD
manthosdid@yahoo.gr
2310994830
Backup
Areti Pagiantza, MD
apayantza@gmail.com
2313303736
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2029-03-01
Participants
Target number of participants: 80
Treatments
Experimental: Intervention
Patients with RAO that will receive Rivaroxaban
No_intervention: Control
Patients with RAO that will not receive any anticoagulation
Related Therapeutic Areas
Sponsors
Leads: AHEPA University Hospital

This content was sourced from clinicaltrials.gov