Comparative Effectiveness of Multi Versus Single Intervention Allergen Reduction Strategies on Asthma Morbidity

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The Allergen Reduction and Child Health Study (ARCHS) is a 12-month, two group randomized control trial of children with asthma and who are exposed to cockroaches. Children ages 5 - 17 living in the Greater New Orleans area will be recruited from a variety of clinic and community settings. The overall goal of the study is to improve patient-centered asthma outcomes (asthma symptom days, health care utilization, asthma control and quality of life) by targeting one key allergen - cockroach exposure in the child's home. The investigators propose a simple intervention of insecticidal bait that is low cost, simple to implement, and which is lower toxicity than other forms of pest control. The reduction in the number of cockroaches in the home is an environmental outcome that is patient-centered and is likely to add to its acceptance by families of children with asthma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 17
Healthy Volunteers: f
View:

• Age 5 - 17 years; with uncontrolled persistent asthma defined as the child experiencing at least one of the following: one overnight hospitalization for asthma within the past six months OR two unscheduled clinic or emergency department visits for asthma within the last 12 months; and either on a long term controller medication for asthma, or have asthma symptoms 3 or more days per week over the past 2 weeks or nighttime asthma symptoms at least 3 times in the past month exposure to cockroach - defined as trapping at least one cockroach in a 3 day period OR visual evidence of cockroaches by field staff; and the child must sleep in the target home at least 4 nights per week on average. Caregiver ability to speak English or Spanish.

Locations
United States
Louisiana
Tulane University
RECRUITING
New Orleans
Contact Information
Primary
Derek Werthmann, PhD
dwrthma@tulane.edu
5049882386
Backup
Joanna Baisier
jbaisier@tulane.edu
5049883430
Time Frame
Start Date: 2020-11-15
Estimated Completion Date: 2028-04-30
Participants
Target number of participants: 290
Treatments
Active_comparator: Comparator 1 (tailored approach)
Multi-component intervention tailored to the participant's allergic profile.
Active_comparator: Comparator 2 (insecticidal bait)
Insecticidal bait for cockroach reduction.
Related Therapeutic Areas
Sponsors
Leads: Tulane University
Collaborators: Patient-Centered Outcomes Research Institute

This content was sourced from clinicaltrials.gov