Asthma Clinical Trials

Find Asthma Clinical Trials Near You

SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• asthmatic patient

• aged 18- 65 years

• ACQ \> 1.5

• stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene

Locations
Other Locations
Belgium
Chu Liege
RECRUITING
Liège
Contact Information
Primary
Stephanie Ziant
sziant@chuliege.be
+3243668568
Time Frame
Start Date: 2020-09-01
Estimated Completion Date: 2028-09-01
Participants
Target number of participants: 100
Treatments
Active_comparator: respiratory physiotherapy
Exercises to improve the way of breathing. The breathing exercise sessions will last 30 minutes and be supervised by a physiotherapist 3 times per week.
No_intervention: control group
No intervention - collection of data at baseline and 3 months without any intervention in between.
Other: Aerobic exercise training
Arm Description: The aerobic training program will be performed indoor three times a week for 12 weeks, under the direct supervision of a chest physician and a physiotherapist. Each aerobic training session will last 75 minutes and will be divided in 5 min of warm-up, 60 min of aerobic training (including 20 minutes on three different ergometers: bicycle, treadmill and rower/elliptical trainers) and 10 min of cool-down. Training intensity is determined by the maximal aerobic power (MAP) previously measured during an initial cardiopulmonary exercise test. Progressive increase in training load during the first three weeks (3x20 minutes at 50% of MAP), followed by 3x20 min at 60% of MAP from weeks 4 to 6, then 3x20 min at 70% of MAP from week 7 to week 9. Finally trainings from week 10 to week 12 include one session of interval training and two sessions of continuous training.
Related Therapeutic Areas
Sponsors
Leads: University of Liege

This content was sourced from clinicaltrials.gov