Taiwan Severe Asthma Biologic Registry

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY

This is a prospective multi-centers cohort study for registration adult patients with severe asthma and were reimbursed biologics treatment in Taiwan. The goal of this observational study is to discover the real-world effectiveness, the impact of initiating, switching of biologics, and the possible prediction factors for selecting the best treatment option for patients. The main question\[s\] it aims to answer are: 1. Determine risk factors associated with poor asthma control. 2. Support the development of effectiveness and safety of therapeutic principles 3. To discover the real-world effectiveness of different biologics ( Clinical remission) 4. To discover the impact of initiating biologics for severe asthma patients. 5. To evaluate the prevalence of biologics switching and its benefits for patients. 6. To compare the achievement rate of clinical remission among different biologics. Participants who are treated either with omalizumab, mepolizumab, benralizumab dupilzumab or Tezepelumab after January 1, 2020 will be included in the study.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Provision of informed consent prior to any study specific procedures.

• Patient should be reviewed as well as confirmed by the National Health Insurance Administration (NHIA) or by the study board member as a Severe Asthma case.

• Female and male aged over 18 years old.

• Patients who are treated either with omalizumab, mepolizumab, or benralizumab after January 1, 2020.

Locations
Other Locations
Taiwan
Taichung Veterans General Hospital
RECRUITING
Taichung
Contact Information
Primary
Pin-Kuei Fu, MD.,PhD.
yetquen@gmail.com
886-4-23592525
Time Frame
Start Date: 2023-11-11
Estimated Completion Date: 2043-02-28
Participants
Target number of participants: 500
Treatments
Omalizumab
Severe asthma patients who are treated with omalizumab after January 1, 2020.
Mepolizumab
Severe asthma patients who are treated with mepolizumab after January 1, 2020.
Benralizumab
Severe asthma patients who are treated with benralizumab after January 1, 2020.
Dupilzumab
Severe asthma patients who are treated with dupilzumab after January 1, 2020.
Tezepelumab
Severe asthma patients who are treated with Tezepelumab after January 1, 2020.
Related Therapeutic Areas
Sponsors
Collaborators: National Yang Ming Chiao Tung University Hospital, National Cheng-Kung University Hospital, E-DA Hospital, Chang Gung Memorial Hospital
Leads: Taichung Veterans General Hospital

This content was sourced from clinicaltrials.gov