Asthma Clinical Trials

Find Asthma Clinical Trials Near You

A Phase 2, Randomized, Double-blind, Placebo-controlled, Multiple Dose-Ranging Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Solrikitug in Adult Participants With Asthma (RAINIER)

Status: Recruiting
Location: See all (74) locations...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Participant must be aged 18 to 75 years of age.

• Documented diagnosis of asthma at least 12 months prior to Screening.

• Participants must be on maintenance asthma medications, for at least 3 months prior to screening: inhaled corticosteroid (ICS) in combination with long-acting beta agonist (LABA), or as part of an approved triple therapy for asthma (ICS/LABA/long-acting muscarinic antagonist \[LAMA\]).

• Participant has an ACQ-6 score ≥1.5 at Screening Visit.

• Participant has FEV1 of ≥50% to 90%, inclusive, of predicted normal value at Screening Visit 1.

• Evidence of asthma as documented by reversibility in FEV1 of ≥12% and ≥200 mL over the pre-salbutamol FEV1 at Screening Visit.

Locations
United States
Alabama
Velocity Clinical Research
RECRUITING
Mobile
Arizona
Phoenix Medical Group
RECRUITING
Peoria
California
Warren W. Pleskow, M.D.
RECRUITING
Encinitas
Beach Physicians Clinical Research Corp.
RECRUITING
Huntington Beach
Biosolutions Clinical Research Center
RECRUITING
La Mesa
Orso Health
RECRUITING
Long Beach
Downtown LA Research Center
RECRUITING
Los Angeles
Newport Native MD, Inc.
RECRUITING
Newport Beach
Prospective Research Innovations Inc.
RECRUITING
Rancho Cucamonga
Allergy & Asthma Medical Group and Research Center
RECRUITING
San Diego
Allergy & Asthma Associates of Santa Clara Valley
RECRUITING
San Jose
San Jose Clinical Trials
RECRUITING
San Jose
North Bay Clinical Research
RECRUITING
Santa Rosa
Providere Research
RECRUITING
West Covina
Colorado
Velocity Clinical Research - Denver
RECRUITING
Englewood
Florida
Clinical Research of West Florida
WITHDRAWN
Clearwater
JY Research Institute
RECRUITING
Cutler Bay
Hillcrest Medical Research, LLC
RECRUITING
Deland
Clinical Site Partners LLC dba-Leesburg
RECRUITING
Leesburg
Coral Research Clinic Corp.
RECRUITING
Miami
Pharmax Research of South Florida
RECRUITING
Miami
Pro-Care Research Center, Corp.
RECRUITING
Miami Gardens
Ogden Clinical Canyon View
RECRUITING
Tallahassee
Care Access, Tamarac
RECRUITING
Tamarac
TBC Research
RECRUITING
Tamarac
Georgia
National Clinical Trials
RECRUITING
Cordele
CPCC - Research, LLC
RECRUITING
East Point
Aeroallergy Research Laboratories of Savannah, Inc.
RECRUITING
Savannah
Iowa
Velocity Clinical Research - Sioux City
RECRUITING
Sioux City
Idaho
NexGen Research
RECRUITING
Boise
Treasure Valley Medical Research
RECRUITING
Boise
Velocity Clinical Research - Boise
WITHDRAWN
Meridian
Illinois
Accellacare - Duly
RECRUITING
Winfield
Indiana
Indiana Medical Research Institute
WITHDRAWN
Merrillville
Louisiana
Velocity Clinical Research
RECRUITING
Lafayette
Massachusetts
Mayflower Clinical
RECRUITING
South Dartmouth
Maryland
Chesapeake Clinical Research, Inc.
RECRUITING
White Marsh
Michigan
Deerborn Clinic
RECRUITING
Dearborn
Henry Ford Health System
RECRUITING
Detroit
Pulmonary Research Institute of SE Michigan
RECRUITING
Farmington Hills
Revive Research Institute, Inc.
RECRUITING
Southfield
Montana
Montana Medical Research, Inc.
RECRUITING
Missoula
North Carolina
Asheville Clinical Research
RECRUITING
Asheville
Clinical Research of Gastonia
WITHDRAWN
Gastonia
North Carolina Clinical Research
RECRUITING
Raleigh
Southeastern Research Center
RECRUITING
Winston-salem
Nevada
Henderson Trials
RECRUITING
Henderson
New York
A1 Clinical
RECRUITING
Queens Village
Ohio
Midwest Clinical Research
RECRUITING
Dayton
Toledo Institute of Clinical Research Inc.
RECRUITING
Toledo
Oklahoma
OK Clinical Research
RECRUITING
Edmond
Oregon
Velocity Clinical Research
RECRUITING
Medford
Northwest Research Center
RECRUITING
Portland
Pennsylvania
Clinical Research Associates of Central PA
RECRUITING
Dubois
Allergy & Asthma Diagnostic Treatment Center
RECRUITING
Lancaster
Temple University - Shenoy
RECRUITING
Philadelphia
South Carolina
Care Access - Mauldin
RECRUITING
Mauldin
Allergy, Asthma & Sinus Center, LLC
RECRUITING
Myrtle Beach
MBR - Charleston
RECRUITING
North Charleston
Clinical Research of Rock Hill
RECRUITING
Rock Hill
Tennessee
Premier Research Center, LLC
RECRUITING
Hendersonville
New Phase Research & Development
RECRUITING
Knoxville
Texas
TTS Research
RECRUITING
Boerne
Proactive RGV
RECRUITING
Brownsville
Ten20 Clinical Research, LLC
RECRUITING
Carrollton
Javarra Research
RECRUITING
Conroe
Dallas Allergy and Asthma Center
RECRUITING
Dallas
IntraCare Health Center
RECRUITING
Dallas
US Allergy & Asthma
RECRUITING
Frisco
IntraCare Clinical
RECRUITING
Greenville
Axsendo Clinical Research
RECRUITING
Houston
Gulf Coast Clinical Research
RECRUITING
Houston
Baylor Scott & White Health
WITHDRAWN
Temple
Virginia
Velocity Clinical Research - Hampton
RECRUITING
Hampton
Contact Information
Primary
Uniquity One Clinical Trials
ClinicalTrials@uniquity.com
484-267-2500
Backup
Anushri Walsh
awalsh@devprobiopharma.com
973-983-3700
Time Frame
Start Date: 2024-07-26
Estimated Completion Date: 2026-09-30
Participants
Target number of participants: 140
Treatments
Experimental: Solrikitug low dose subcutaneous injection
Solrikitug
Experimental: Solrikitug mid dose subcutaneous injection
Solrikitug
Experimental: Solrikitug high dose subcutaneous injection
Solrikitug
Placebo_comparator: Placebo subcutaneous injection
Placebo
Related Therapeutic Areas
Sponsors
Collaborators: DevPro Biopharma
Leads: Uniquity One (UNI)

This content was sourced from clinicaltrials.gov