Clinical Assessment of Jia Wei Yang He Formula as a Plus Therapy in the Treatment of Persistent Asthma and Airway Microbiome Exploration Research
Who is this study for? Adult patients with Bronchial Asthma
What treatments are being studied? Jia Wei Yang He
Status: Recruiting
Location: See all (8) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY
Investigators aimed to assess Jia Wei Yang He Formula as a plus therapy in the treatment of persistent asthma and to explore Airway Microbiome variation of Asthma by Traditional Chinese Medicine treatment
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Patient diagnosed with chronic persistent asthma
• Annual uncontrollable time ≥ 3 months
• Patients who have given written informed consent
Locations
Other Locations
China
Fengxian District traditional Chinese medicine hospital
NOT_YET_RECRUITING
Shanghai
Jingan district center hospital
NOT_YET_RECRUITING
Shanghai
Longhua Hospital Affiliated Shanghai University of TCM
RECRUITING
Shanghai
Pudong Hospital
NOT_YET_RECRUITING
Shanghai
Shanghai eighth people's hospital
NOT_YET_RECRUITING
Shanghai
Shanghai TCM-Integrated Hospital
NOT_YET_RECRUITING
Shanghai
Xuhui district center hospita
NOT_YET_RECRUITING
Shanghai
Zhongshan Hospital affiliated fudan university
NOT_YET_RECRUITING
Shanghai
Contact Information
Primary
Zifeng Ma, Master
mzf05@126.com
+8621-64385700
Backup
Zhenhui Lu, Doctor
tcmdoctorlu@163.com
+8621-64385700
Time Frame
Start Date: 2017-10-01
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 240
Treatments
Placebo_comparator: Control Group
80 participants will take oral therapy of 9.25 g Jia Wei Yang He granule Placebo twice a day for 28 consecutive days and also standard therapy of inhaled corticosteroid or beta2-agonist.
Experimental: High dose Treatment Group
Participants in high Jia Wei Yang He formula group will receive Jia Wei Yang He granule 18.5g twice a day for 28 consecutive days and also standard therapy of inhaled corticosteroid or beta2-agonist.
Experimental: Low dose Treatment Group
Participants in high Jia Wei Yang He formula group will receive Jia Wei Yang He granule 9.25g twice a day for 28 consecutive days and also standard therapy of inhaled corticosteroid or beta2-agonist.
Related Therapeutic Areas
Sponsors
Collaborators: Fudan University
Leads: Shanghai University of Traditional Chinese Medicine