Natural History of Coronary Atherosclerosis Based on Multimodal Imaging and Physiological Fusion Techniques (NASCENT)

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The present study sought to explore the predictive value of radial wall strain (RWS, derived solely from angiograms) for coronary artery lesion progression compared with lesion vulnerability assessed by optical coherence tomography (OCT). The lesion progression at 1 year was defined as an increase of ≥20% in diameter stenosis based on quantitative coronary angiography (QCA) evaluation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• General Inclusion Criteria:

‣ Age ≥18 years

⁃ Acute myocardial infarction ≤ 45 days

⁃ Planned coronary angiography examination or potential interventional treatment

• Angiographic Inclusion Criteria:

‣ The presence of at least 1 non-flow-restricting lesion (visually estimated diameter stenosis: 30%-80%; QFR \> 0.80) in any non-infarct related artery with RVD ≥2.5 mm by visual assessment

Locations
Other Locations
China
Lei Song
RECRUITING
Beijing
Contact Information
Primary
Lei Song, MD
drsong@vip.163.com
01088322564
Time Frame
Start Date: 2024-07-07
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 125
Related Therapeutic Areas
Sponsors
Leads: China National Center for Cardiovascular Diseases

This content was sourced from clinicaltrials.gov