The Role of Inflammation in Vascular Disease (Inflammationens Roll i kärlsjukdom)
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Increasing evidence suggests that systemic low-grade inflammation may be a driving force of cardiometabolic complications, such as vascular dysfunction, atherosclerosis and ischemic heart disease. Thus, we will investigate the role of inflammation in cardiovascular disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Patient is planned to undergo vascular surgery.
• Signed informed consent has been obtained from the patient.
Locations
Other Locations
Sweden
University of Gothenburg
RECRUITING
Gothenburg
Contact Information
Primary
Emma Borgeson, PhD
emma.borgeson@wlab.gu.se
+46313420000
Backup
Per Skoog, MD, PhD
per.skoog@vgregion.se
+46313420000
Time Frame
Start Date: 2019-09-02
Estimated Completion Date: 2027-02-01
Participants
Target number of participants: 170
Treatments
Control patients
Control patients (n=20): In individuals undergoing vascular surgery that is not associated with vascular disease (e.g. knee replacement surgery, trauma, etc), a piece of healthy vessel must sometimes be removed in order to facilitate the surgical process. The vessel biopsies from this group will be categorized as healthy vessels in our study.
Study patients
Study patients (n=150): In individuals undergoing vascular surgery associated with peripheral arterial diseases, aneurysm and/or other manifestations of atherosclerosis, vascular tissue is sometimes excised to facilitate the surgery. Biopsies from these individuals will be categorized as vessels with vascular dysfunction.
Related Therapeutic Areas
Sponsors
Leads: Göteborg University