An Open Label, Parallel Group Comparison Study To Evaluate the Safety Tolerability, and Pharmacokinetics of UHE-103 Cream Versus Naftin Cream in Subjects With Tinea Cruris and/or Tinea Pedis Under Maximal Use Conditions

Status: Completed
Location: See all (5) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

This Phase 1 study has been designed to determine the safety, tolerability and pharmacokinetics (PK) of UHE 103 Cream compared to Naftin Cream, 2% under maximal use conditions for 2 weeks treatment in subjects with tinea cruris and/or tinea pedis

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
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• Subject is a male or non-pregnant female 18 years of age or older.

• Subject has provided written informed consent.

• Subject has a clinical diagnosis of moccasin-type tinea pedis with at least moderate scaling on at least 1 foot at Visit 1/Screening;

• Subject has a clinical diagnosis of interdigital tinea pedis with at least moderate scaling on at least 1 foot (without moccasin-type tinea pedis) and tinea cruris at Visit 1/Screening.

• Subject is willing and able to apply the test article(s) as directed, comply with study instructions, and commit to all follow-up visits for the duration of the study.

Locations
United States
California
Site #1
San Diego
Site #5
Thousand Oaks
Texas
Site #2
Austin
Site #3
College Station
Site #4
Houston
Time Frame
Start Date: 2022-02-17
Completion Date: 2023-11-14
Participants
Target number of participants: 42
Treatments
Experimental: UHE-103 Cream
Subjects will apply at least a total of 4 grams\* of the test article, covering both feet twice daily for 2 weeks
Active_comparator: Naftin (naftifine hydrochloride) Cream, 2%
Subjects will apply at least a total of 5 grams\* of the test article, covering the interdigital areas of both feet and to the groin once daily for 2 weeks
Related Therapeutic Areas
Sponsors
Leads: Therapeutics, Inc.

This content was sourced from clinicaltrials.gov