Becker Muscular Dystrophy Clinical Trials

Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder predominantly affecting boys and men, with an estimated incidence of 1 in 3,800 to 1 in 6,200 live male births. This condition leads to progressive muscle weakness due to the absence of the dystrophin protein, which is essential for maintaining muscle cell integrity. Symptoms and functional impairments typically become apparent by the age of two, and individuals with DMD have an average life expectancy of around 28 years. Treatment is generally multifaceted, focusing on enhancing quality of life (QOL) and postural control. The Alexander technique is employed to improve QOL and postural tone, as well as to modify body schema, with reported benefits from these changes. This method leverages spatial attention and executive functions that influence basic motor skills through targeted attention, intention, and haptic communication, thereby enhancing the QOL and postural control of the upper limbs. The aim of the study is to determine the effects of Alexander's technique on postural control of upper limb and quality of life in children with duchenne muscular dystrophy.