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Early Oral Feeding Versus Conventional Feeding After Surgery for Biliary Atresia and Choledochal Cyst: A Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to compare two feeding approaches after surgery for biliary atresia and choledochal cyst in children. Traditionally, children are kept without oral feeding for more than 48 hours after these operations until bowel activity returns. However, newer Enhanced Recovery After Surgery (ERAS) programs suggest that starting feeding earlier may help children recover faster. In this study, children undergoing surgery for biliary atresia or choledochal cyst will be randomly assigned to one of two groups. One group will start oral liquids within 24 hours after surgery and gradually progress to normal feeding as tolerated (early feeding group). The other group will receive conventional care, where feeding is started after more than 48 hours once bowel activity has returned. Researchers will compare both groups for postoperative complications such as wound infection and anastomotic leakage, as well as the duration of hospital stay. Additional observations will include vomiting, abdominal distension, need for reinsertion of a nasogastric tube, requirement for repeat surgery, and time taken to resume normal feeding. Participation in the study will not affect the standard surgical treatment provided. All children will receive routine perioperative care and will be monitored closely throughout their hospital stay and follow-up visits. The findings of this study may help determine whether early oral feeding is a safe and effective strategy to improve recovery and reduce hospitalization after pediatric hepatobiliary surgery.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 1 month
Maximum Age: 14
Healthy Volunteers: f
View:

• All children diagnosed with choledochal cyst type I and IV on MRCP or CT scan, undergoing elective Roux-En-Y hepaticojejunostomy

• All children with provisional diagnosis of biliary atresia undergoing Roux-En-Y portoenterostomy

Locations
Other Locations
Pakistan
University of Child Health Sciences, The Children's Hospital, Lahore
RECRUITING
Lahore
Contact Information
Primary
Sundas Zahra, MBBS
sundaszahra1080@gmail.com
+923400686300
Backup
Muhammad Zubair Shoukat, MBBS, FCPS Pediatric Surgery
zubairshaukat@outlook.com
03126446646
Time Frame
Start Date: 2024-07-27
Estimated Completion Date: 2026-08
Participants
Target number of participants: 100
Treatments
Experimental: ERAS Feeding Protocol in Choledochal Cyst
The patients with Roux-en-Y hepaticojejunostomy for choledochal cyst will be started oral liquids within 24 hours of surgery, NG Tube will be removed before starting oral feeds
Active_comparator: Conventional Feeding Protocol in Choledochal Cyst
The post operative patients of Roux-en-Y hepaticojejunostomy for choledochal cyst will be allowed oral liquids after confirmation of resumption of bowel function (Positive bowel sounds, passage of stool or flatus, clear NG aspirate)
Experimental: ERAS in Biliary Atresia
Post-op patients of Roux-en-Y portoenterostomy for biliary atresia will be allowed oral liquids within 24 hours of surgery and NG tube will be removed.
Active_comparator: Conventional feeding protocol in Biliary Atresia
Post-op patients of portoenterostomy for biliary atresia will be allowed oral feeds only after confirmation of bowel functions (positive bowel sounds, passage of stool or flatus, clearing of NG aspirate)
Related Therapeutic Areas
Sponsors
Collaborators: University of Child Health Sciences and Children's Hospital, Lahore
Leads: Muhammad Zubair Shoukat

This content was sourced from clinicaltrials.gov

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