Basal Plasma Lithium Levels and Suicidal Events (LIPS)

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Observational
SUMMARY

Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk. Apart from drug treatments, lithium is present in our environment and its levels varies from one individual to another, depending, especially, on diet. Knowing that patients with a mood disorder generally have a poor lifestyle and a less rich and varied diet than the general population, variations in basal lithium levels can be expected in these patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 18 years old or over

• Current major depressive episode according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria

• No lithium-based treatment over the last 12 months

• For suicide attempters/ideations only : suicidal event over the last 12 months

• For affective controls only : no suicidal event over the last 12 months

Locations
Other Locations
France
CHU Montpellier
RECRUITING
Montpellier
Contact Information
Primary
Bénédicte NOBILE, Pharma D, PhD
b-nobile@chu-montpellier.fr
+33467338581
Time Frame
Start Date: 2022-12-09
Estimated Completion Date: 2027-01-09
Participants
Target number of participants: 158
Treatments
Suicide attempters/ideations
Patients currently suffering from a major depressive disorder and reporting at least one suicidal event (suicide attempt or hospitalization for suicidal ideation) over the last 12 months.
Affective controls
Patients currently suffering from a major depressive disorder and reporting no suicidal event (suicide attempt or hospitalization for suicidal ideation) over the last 12 months.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Montpellier

This content was sourced from clinicaltrials.gov