Basal Plasma Lithium Levels and Suicidal Events (LIPS)
Suicidal behavior is a major public health issue and there are currently no specific treatments for it. However, lithium, the reference treatment for bipolar disorder, have been shown to be effective in preventing suicidal risk. Apart from drug treatments, lithium is present in our environment and its levels varies from one individual to another, depending, especially, on diet. Knowing that patients with a mood disorder generally have a poor lifestyle and a less rich and varied diet than the general population, variations in basal lithium levels can be expected in these patients.
• 18 years old or over
• Current major depressive episode according to the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders) criteria
• No lithium-based treatment over the last 12 months
• For suicide attempters/ideations only : suicidal event over the last 12 months
• For affective controls only : no suicidal event over the last 12 months