Study on the Mechanism of Action of Chemical Category 1 Innovative Drug GMDTC on Neuropsychiatric Behavior in Cadmium-exposed People
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
This study hypothesized that excessive cadmium is related to clinical pain, depression, and cognitive impairment, and that related indicators will improve after cadmium is eliminated.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
⁃ Age ≥18 years old, both men and women are welcome
⁃ The weight of male subjects is ≥50.0 kg, the weight of female subjects is ≥45.0 kg, and the body mass index (BMI) is between 19 \
• 26 kg/m2, including the critical value
⁃ Urinary cadmium \>5 μmol/mol creatinine for 2 consecutive days (creatinine content is ≥0.3 μg/L and ≤3 μg/L)
⁃ Right-handed
⁃ Voluntarily participate in this study and sign informed consent.
Locations
Other Locations
China
Hunan Occupational Disease Prevention and Control Institute
RECRUITING
Changsha
Contact Information
Primary
Xiaojiang Tang, PhD
river-t@126.com
13719282259
Backup
Rong Ma
gynkmarong@163.com
17685224168
Time Frame
Start Date: 2024-01-08
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 84
Treatments
Cadmium exceeding standard group
The urine cadmium level exceeding 5 μg/g creatinine for two consecutive times.
healthy control group
Urine cadmium ≤ 5 μg/g creatinine.
Related Therapeutic Areas
Sponsors
Leads: Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.