Application Research of FAPI Positron Emission Tomography(PET)/MRI, 18F-Fluorodeoxyglucose (FDG) PET/MRI, and MRI in the Diagnosis of Muscular Invasive Bladder Cancer and Evaluation of Neoadjuvant Therapy Efficacy
Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this trial is to investigate the value of FAPI PET/MRI, FDG PET/MRI and MRI in diagnosing MIBC and predicting the efficacy of neoadjuvant therapy for MIBC patients, so as to guide the clinic to adjust the treatment plan in time and benefit MIBC patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Inclusion criteria for MIBC diagnostic studies
‣ Patients with suspected muscle-invasive bladder cancer;
⁃ Completion of FAPI PET/MRI, FDG PET/MRI and MRI;
⁃ Complete clinical laboratory and pathological data.
• Inclusion criteria for MIBC neoadjuvant therapy efficacy evaluation study
‣ Patients diagnosed with muscle invasive bladder cancer;
⁃ Completion of FAPI PET/MRI, FDG PET/MRI, and MRI before neoadjuvant therapy;
⁃ Complete clinical laboratory and pathological data.
Locations
Other Locations
China
first hospital affiliated of Fujian medical university
RECRUITING
Fuzhou
Contact Information
Primary
Ning Xu, Doctor
drxun@fjmu.edu.cn
13235907575
Backup
Xiao-Dong Li, Master
lixiaodong@fjmu.edu.cn
15980273075
Time Frame
Start Date: 2024-08-02
Estimated Completion Date: 2029-06-01
Participants
Target number of participants: 80
Treatments
Experimental: MIBC diagnostic study-FAPI PET/MRI
suspected MIBC participants receive FAPI PET/MRI examination after entering the group.
Experimental: MIBC diagnostic study-FDG PET/MRI
suspected MIBC participants receive FDG PET/MRI examination after entering the group.
Active_comparator: MIBC diagnostic study-MRI
suspected MIBC participants receive MRI examination after entering the group.
Experimental: MIBC neoadjuvant evaluation study-FAPI PET/MRI
Patients diagnosed with MIBC receive FAPI PET/MRI examination before and after neoadjuvant therapy.
Experimental: MIBC neoadjuvant evaluation study-FDG PET/MRI
Patients diagnosed with MIBC receive FDG PET/MRI examination before and after neoadjuvant therapy.
Active_comparator: MIBC neoadjuvant evaluation study-MRI
Patients diagnosed with MIBC receive MRI examination before and after neoadjuvant therapy.
Related Therapeutic Areas
Sponsors
Leads: First Affiliated Hospital of Fujian Medical University