Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test, Other
Study Type: Observational
SUMMARY
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
Maximum Age: 13
Healthy Volunteers: f
View:
• Children aged 5-13 years old
• A history of cancer
• Treatment with a chemotherapy regimen including VCR and/or DOX
• Completion of chemotherapy at least one year prior to study enrollment and survey completion.
Locations
United States
Colorado
Children's Hospital Colorado
RECRUITING
Aurora
Contact Information
Primary
Gemma Beltran
gemma.beltran@childrenscolorado.org
(720) 777-4418
Time Frame
Start Date: 2021-06-02
Estimated Completion Date: 2026-07-09
Participants
Target number of participants: 152
Treatments
Male Cancer Survivors with DVSS Score ≥ 9
Childhood cancer survivors treated with DOX and/or VCR with evidence of BD on DVSS
Female Cancer Survivors with DVSS Score ≥ 6
Childhood cancer survivors treated with DOX and/or VCR with evidence of BD on DVSS
Male Cancer Survivors with DVSS Score < 9
Childhood cancer survivors treated with DOX and/or VCR without evidence of BD on DVSS
Female Cancer Survivors with DVSS Score < 6
Childhood cancer survivors treated with DOX and/or VCR without evidence of BD on DVSS
Related Therapeutic Areas
Sponsors
Collaborators: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Children's Hospital Colorado, National Cancer Institute (NCI)
Leads: University of Colorado, Denver