Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer of the Bladder and Kidney
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The purpose of this study is to determine if analysis of DNA and protein material found in urine will be useful in the detection of urothelial cancer of the bladder and kidney. This analysis may be helpful to determine if how a particular cancer will act regarding remission and recurrence
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:
• Patients scheduled to have a nephroureterectomy, cystectomy, cytoscopy (newly diagnosed bladder cancer and those with recurrent disease in follow up)
• Control Group: No known evidence of bladder cancer-one urine sample
• \> than 18 years of age
Locations
United States
Massachusetts
Lahey Clinic, Inc.
RECRUITING
Burlington
Contact Information
Primary
Kimberly Rieger-Christ, PhD
Kimberly.R.Christ@lahey.org
781-744-2969
Backup
Linda M. Topjian
Linda.M.Topjian@Lahey.org
781-744-8711
Time Frame
Start Date: 2002-09
Estimated Completion Date: 2025-11
Participants
Target number of participants: 500
Treatments
1
Bladder Cancer Group:~Patients scheduled to have a cystectomy or cystoscopy of their bladder with possible removal or biopsy of bladder tumor or tissue.~Two urine samples collected at the time of the scheduled procedure:~One sample collected through voiding. The other sample collected from atheterized urine in the operating room. Additional urine samples may be collected at each follow up visit over two years. These samples will be obtained via voiding, standard urine sample collection.
2
Control Group: Patients with no known evidence of bladder cancer. One urine sample will be collected through voiding, as with standard urine sample collection at the time of clinic visit.
Authors
Leonard Zinman
Related Therapeutic Areas
Sponsors
Leads: Lahey Clinic