Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this clinical trial is to use urine tumor DNA (utDNA) as an indicator for non-muscle invasive bladder cancer to identify patients suitable for less frequent cystoscopy surveillance.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• AUA high-risk bladder cancer1
• Received induction BCG or gemcitabine/docetaxel
• Negative initial post-induction therapy assessment (negative cytology and cystoscopy +/- biopsy)
Locations
United States
Massachusetts
Lahey Hospital and Medical Center
RECRUITING
Burlington
Contact Information
Primary
Linda Topjian
Linda.M.Topjian@lahey.org
7817448420
Backup
Colette Osborne
Colette.A.Osborne@lahey.org
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2029-01-01
Participants
Target number of participants: 56
Treatments
Experimental: De-Intensified Arm
Less-frequent cystoscopy surveillance
No_intervention: Standard Surveillance Arm
Regular follow-ups and standard care
Related Therapeutic Areas
Sponsors
Leads: Lahey Clinic