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Pelvic Health Electrically Evoked Recording (PEER) 2 Study

Status: Recruiting
Location: See all (7) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

To collect physiological signals at several timepoints during the therapy evaluation period.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Overactive Bladder Criteria Inclusion Criteria

• 18 years of age or older

• Candidate for or undergoing Medtronic InterStim lead implant for labeled indication\* requiring an advanced evaluation

• Willing and able to provide signed and dated informed consent

• Willing and able to independently and accurately complete diaries, questionnaires, attend visits, and comply with the study protocol

• Willing to maintain current regimen (dosage and frequency) of any OAB medication from baseline diary through the end of therapy evaluation

• For subjects with urinary urge incontinence, have a diagnosis of OAB as demonstrated on a voiding diary by having a minimum of 3 episodes of urinary urge incontinence in the first 72 hours (Episodes must have a mild, moderate, or severe degree of urgency to meet this criterion) of the voiding diary.

• For subjects with urinary frequency, have a diagnosis of OAB as demonstrated on a voiding diary with greater than or equal to 8 urgency frequency episodes per day within the first 72 hours of the voiding diary.

⁃ Note\*: Candidate for or undergoing a Medtronic InterStim lead implant for labeled indication means that a clinical decision has already been made between a physician and the patient to undergo Medtronic Interstim lead implant to treat the subject's condition. This decision is to be made prior to discussing with the patient whether to enroll in the study.

⁃ Non-Obstructive Urinary Retention Inclusion Criteria

• 18 years of age or older

• Candidate for or undergoing Medtronic InterStim lead implant for labeled indication\* requiring an advanced evaluation

• Willing and able to provide signed and dated informed consent

• Willing and able to independently and accurately complete diaries, questionnaires, attend visits, and comply with the study protocol

• Willing to maintain current regimen (dosage and frequency) of any NOUR medication from baseline diary through the end of therapy evaluation

• Have a diagnosis of non-obstructive urinary retention with an elevated postvoid residual (PVR) that has persisted for at least six months and is documented on two or more separate occasions.

⁃ Note\*: Candidate for or undergoing a Medtronic InterStim lead implant for labeled indication means that a clinical decision has already been made between a physician and the patient to undergo Medtronic Interstim lead implant to treat the subject's condition. This decision is to be made prior to discussing with the patient whether to enroll in the study.

⁃ Fecal Incontinence Inclusion Criteria

• 18 years of age or older

• Candidate for or undergoing Medtronic InterStim lead implant labeled indication\* requiring an advanced evaluation

• Willing and able to provide signed and dated informed consent

• Willing and able to independently and accurately complete diaries, questionnaires, attend visits, and comply with the study protocol

• Willing to maintain current regimen (dosage and frequency) of any FI medication from baseline diary through the end of therapy evaluation

• Have a diagnosis of fecal incontinence as demonstrated by 3-day a bowel diary as greater than or equal to 1 incontinent episode of more than staining (i.e., either slight, moderate, or severe soiling)

⁃ Note\*: Candidate for or undergoing a Medtronic InterStim lead implant for labeled indication means that a clinical decision has already been made between a physician and the patient to undergo Medtronic Interstim lead implant to treat the subject's condition. This decision is to be made prior to discussing with the patient whether to enroll in the study.

Locations
United States
Indiana
Indiana University Health Methodist Research Institute
RECRUITING
Indianapolis
Louisiana
LSUHSC Department of Urology
WITHDRAWN
New Orleans
Ochsner Clinic Foundation
RECRUITING
New Orleans
Minnesota
Mayo Clinic Urology/Urogynecology Department
RECRUITING
Rochester
Ohio
University Hospitals Cleveland Medical Center
RECRUITING
Cleveland
OhioHealth Physician's Group Urology
RECRUITING
Hilliard
Texas
DHR Health Institute for Research and Development
COMPLETED
Edinburg
Contact Information
Primary
Katherine Peterson
katherine.r.peterson@medtronic.com
414-704-4065
Time Frame
Start Date: 2022-01-18
Estimated Completion Date: 2026-12-18
Participants
Target number of participants: 300
Treatments
Experimental: Pelvic health Electrically Evoked Recording (PEER) 2 Study
Collect physiological signals
Related Therapeutic Areas
Sponsors
Leads: MedtronicNeuro

This content was sourced from clinicaltrials.gov

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