Assessment of Reorganization and Plasticity of Eloquent Function in Patients With Brain Tumors

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

Purpose of the study: AIM 1: Prospectively collect pre-operative \[functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)\] and intra-operative mapping data in patients with intra-axial brain tumors to assess how well each modality predicts the location of eloquent brain function. In addition, each modality will be compared with the other. AIM 2: Assess reorganization of eloquent brain function and plasticity in patients with intra-axial brain tumors. This will be accomplished by prospectively collecting post-operative mapping studies and neuropsychological tests to compare them to prior mapping studies as stated above.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
View:

• 19 years and older

• Brain tumor in or near eloquent brain regions that is appropriate for attempted resection

• Appropriate body habitus and mental status/capacity to participate with non-invasive or invasive mapping

• Benign or malignant intra-axial brain tumor

• Primary or metastatic intra-axial brain tumor

Locations
United States
Nebraska
University of Nebraska Medical Center
RECRUITING
Omaha
Contact Information
Primary
Dulce Maroni, PhD
dmaroni@unmc.edu
402-836-9751
Backup
Katie Maire, MS
kmaire@unmc.edu
402-559-6895
Time Frame
Start Date: 2012-01-31
Estimated Completion Date: 2027-12
Participants
Target number of participants: 75
Treatments
Eloquent area tumor
Standard of care with brain mapping, pre-, intra-, and post-operative.
Related Therapeutic Areas
Sponsors
Leads: University of Nebraska

This content was sourced from clinicaltrials.gov