Effects of a Physical Exercise Intervention at the Molecular Systemic and Tumor Level Performed During Neoadjuvant Chemotherapy in Women With Breast Cancer
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
To assess in women with triple-negative breast cancer receiving neo-adjuvant chemotherapy the effects of an intense physical exercise program (intervention group) on physical capacity, compared with a control group not meeting the minimum exercise recommendations of the World Health Organization (WHO).
Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Maximum Age: 75
Healthy Volunteers: f
View:
• Diagnosed with breast carcinoma in the 'Hospital Universitario Quirónsalud de Pozuelo' (Madrid, Spain) and following neoadjuvant therapy in the aforementioned center.
• Must have triple negative breast cancer (i.e., negative for estrogen receptors, progesterone receptors, and excess HER2 protein) of size \> or equal to 15 mm
Locations
Other Locations
Spain
Hospital Universitario Quirónsalud de Pozuelo (HUQP)
RECRUITING
Madrid
Lgcortijo@Gmail.Com
RECRUITING
Madrid
Time Frame
Start Date: 2020-01-01
Estimated Completion Date: 2026-12-01
Participants
Target number of participants: 80
Treatments
Experimental: Exercise
The patients in this arm will follow an exercise program for 24 weeks (i.e., during neo-adjuvant treatment), with two sessions per week including both aerobic and resistance training. Exercise intensity will range between 65% and 100% of the maximum score in the scale of Rated Perceived Exertion (RPE).
Other: Control
The patients follow their usual habits as well as a Yoga program. They will also receive educational sessions on the benefits of regular physical activity (brisk walking).
Related Therapeutic Areas
Sponsors
Leads: Universidad Europea de Madrid