A Master Protocol Empowering Mechanobiology Translation Research in Breast Cancer
Status: Recruiting
Location: See all (10) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
METAMECH is a master observational protocol designed to empower a bi-directional collaboration between basic and clinical research, an essential prerequisite to feed and implement precision oncology. METAMECH will follow a stage-mixed cohort of at least 500 patients through their course of treatments, until death or a minimum of 5 years. Patients will be longitudinally sampled and matched clinical data (including imaging) will be collected. Via a multi-tiered informed consensus process, METAMECH will also allow to develop companion diagnostics for molecular enrichment strategies in AIRC-driven proof-of-concept trials.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Verification that the patient could not be reached for informed consent in accordance with applicable national regulations or, alternatively, TIER1 written Informed consent.
• Patients ≥18 years of age.
• Previous diagnosis of breast cancer, or a strong suspicion of BC based on clinical and radiological findings.
• ECOG Performance status \< 2 (only for TIER1-2).
Locations
Other Locations
Italy
Asst Papa Giovanni Xxiii
NOT_YET_RECRUITING
Bergamo
Fondazione IRCCS, Istituto Nazionale dei Tumori
RECRUITING
Milan
Fondazione IRCCS, Istituto Neurologico Carlo Besta
RECRUITING
Milan
IEO - Istituto Europeo di Oncologia
RECRUITING
Milan
IRCCS Humanitas
RECRUITING
Milan
Azienda Ospedaliero Universitaria Maggiore della Carità di Novara
RECRUITING
Novara
Istituto Oncologico Veneto IRCCS (IOV)
RECRUITING
Padua
Fondazione IRCCS, Policlinico San Matteo Pavia
RECRUITING
Pavia
Azienda U.S.L. - IRCCS di Reggio Emilia
RECRUITING
Reggio Emilia
Istituto Nazionale Tumori Regina Elena di Roma - Istituti Fisioterapici Ospitalieri (IFO)
RECRUITING
Roma
Contact Information
Primary
Smeralda Rapisarda
clinical.trials@ifom.eu
+3902574303236
Backup
Ylenia Silvestri, PhD
clinical.trials@ifom.eu
+3902574303799
Time Frame
Start Date:2020-07-16
Estimated Completion Date:2026-12
Participants
Target number of participants:1500
Treatments
Cohort of BC patients
Stage-mixed cohort of at least 1500 breast cancer patients through their course of treatment, until death or a minimum of 5 years.