Neurobiological and Psychological Maintenance Mechanisms Associated With Anticipatory Reward in Bulimia Nervosa

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The purpose of this investigation is to identify the potentially crucial role of anticipatory reward mechanisms maintaining bulimic behavior (i.e., binge eating and purging) in bulimia nervosa (BN). The research will investigate neural and psychological anticipatory processes in BN, both in the scanner and the natural environment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: t
View:

⁃ Bulimia nervosa (BN) and healthy control (HC) groups:

• Right-handed

• Ability to read and speak in English

⁃ BN group only:

• Eating Disorder Examination (EDE) diagnosis of BN (i.e., at least one objective bulimic episode and one self-induced vomiting episode per week for at three months) with binge episodes always accompanied by self-induced vomiting

• Stable dose for at least 6 weeks of any recent changes in medication impacting mood, appetite, or weight

⁃ HC group only:

• No binge eating or purging episodes for the past three months on the EDE

• No current or past history of an eating disorder as diagnosed by Structured Clinical Interview for DSM-5 Disorders

Locations
United States
Minnesota
University of Minnesota
RECRUITING
Minneapolis
Contact Information
Primary
Carol B Peterson, PhD
peter161@umn.edu
(612)-273-9811
Time Frame
Start Date: 2022-04-01
Estimated Completion Date: 2025-11-30
Participants
Target number of participants: 100
Treatments
Bulimia Nervosa
Participants with diagnosed bulimia nervosa (BN) who will complete all tasks during Visits 1 and 2 in addition to ecological momentary assessment (EMA) procedures following Visit 2.
Healthy Control
Participants without diagnosed BN or other current or past eating disorders who will complete all tasks during Visits 1 and 2 and will not complete EMA procedures following Visit 2.
Related Therapeutic Areas
Sponsors
Leads: University of Minnesota

This content was sourced from clinicaltrials.gov